Metabolic Engineering: Principles and Methodologies by George Stephanopoulos,Aristos A. Aristidou,Jens Nielsen

By George Stephanopoulos,Aristos A. Aristidou,Jens Nielsen

Metabolic engineering is a brand new box with purposes within the construction of chemical compounds, fuels, fabrics, prescription drugs, and drugs on the genetic point. The field's novelty is within the synthesis of molecular biology innovations and the instruments of mathematical research, which enable rational choice of ambitions for genetic amendment via measurements and keep an eye on of metabolic fluxes. the target is to spot particular genetics or environmental manipulations that bring about advancements in yield and productivities of biotechnological processes.

Key positive factors of the booklet are pathway integration and the point of interest on metabolic flux as a basic determinant of phone body structure. The booklet retains mathematical complexity to a minimal, and offers a thesaurus of organic phrases to facilitate use of the booklet by way of a broader spectrum of readers. an internet web page exists to speak updates of the codes and homework problems.

  • Demonstrates metabolic engineering in motion with various examples of pathway modification
  • Includes tools for choosing key enzymes in metabolic networks
  • Contains a finished evaluate of metabolic biochemistry
  • Discusses metabolic rules on the gene, enzyme, operon, and mobile levels
  • Explains suggestions of stoichiometry, kinetics, and thermodynamics of metabolic pathways
  • Minimizes mathematical complexity
  • Links to an online web page to speak updates of the software program code and homework problems

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